Pennsaid (diclofenac topical 1.5% solution) is used to treat pain in the knees caused by osteoarthritis.
Pennsaid Solution may also be prescribed for purposes not listed in this medication guide.
Before you use Pennsaid...
Do not use Pennsaid just before or after heart bypass surgery.
Pennsaid can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease.
Do not use Pennsaid in the last 3 months of pregnancy.
Avoid drinking alcohol when using Pennsaid.
Dosages of Pennsaid varies by patient. Use Pennsaid exactly as prescribed by your doctor and/or the directions on your prescription label.
Apply the solution only to clean, dry skin. Spread the solution over the front, back, and sides of the knee (if prescribed to the knee).
Wash your hands after applying Pennsaid, unless you are treating the skin on your hands. Wait at least 10 minutes before dressing or wearing gloves. Wait at least 1 hour before you bathe or shower.
Do not apply Pennsaid to an open skin wound, or on areas of infection, rash, or burn.
If you miss a dose of Pennsaid, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
If you suspect you may have overdosed on Pennsaid, or are having an allergic reaction the medication, seek medical attention immediately.
Less serious side effects include:
-indigestion, gas, stomach pain, nausea, vomiting
-headache, dizziness, drowsiness
-itching, increased sweating
-increased blood pressure
-swelling or pain in your arms or legs
Serious side effects include:
-the first sign of any skin rash, no matter how mild
-shortness of breath (even with mild exertion)
-swelling or rapid weight gain
-signs of stomach bleeding (e.g., bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds)
-liver problems (nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice)
-kidney problems (little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath)
-high blood pressure (severe headache, pounding in your neck or ears, nosebleed, anxiety, confusion)
-low red blood cells (anemia; pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating)
-severe skin reaction (fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads, and causes blistering and peeling)
This is not a complete list of all side effects. If you experience serious side effects, contact a doctor or your nearest hospital immediately.
There are drugs that interact with Pennsaid. You should tell your doctor about all of the medications you use, including prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should always tell your doctor before you start taking new medication.